49ers, Jaguars Face Key Injuries Ahead Week 4 NFL Clash

The San Francisco 49ers face significant injury challenges heading into their Week 4 game against the Jacksonville Jaguars, with key players like tight end George Kittle (hamstring), wide receivers Brandon Aiyuk and Ricky Pearsall (knee soreness), and edge rusher Nick Bosa (season-ending ACL) sidelined. Quarterback Brock Purdy is expected to return, but backup Mac Jones remains questionable due to a knee injury. The receiving corps is notably depleted, although rookie Pearsall remains optimistic about playing despite knee soreness, and Demarcus Robinson is set to debut after suspension. On the Jaguars' side, wide receiver Dyami Brown, who left last week's game with a shoulder injury, is limited but expected to play, which is crucial given Jacksonville's receiver depth concerns. The Jaguars maintain confidence in their receiving unit despite injuries, with players like Travis Hunter and Parker Washington ready to step up if needed. Both teams are managing injuries strategically to improve their chances in this pivotal matchup.