The Chicago Cubs and Minnesota Twins are set for an interleague matchup, with the Twins entering on a four-game winning streak, averaging 9.25 runs per game. Minnesota's lineup recently produced a significant 13-7 victory, led by standout performances from Willi Castro and Jose Miranda, while rookie David Festa looks to stabilize their pitching as he faces Chicago for the first time. The Cubs, who recently defeated the St. Louis Cardinals 6-2, are aiming to improve their postseason chances, sitting six games behind the wild-card spot. Despite a challenging season, the Cubs recently achieved a balanced run differential of 0, a notable improvement after a negative trend earlier in the season. Meanwhile, the Chicago White Sox are struggling with a historic 20-game losing streak, matching the third-longest in MLB history, as they prepare for what may be their final series at the Oakland Coliseum. The franchise faces significant pressure to rebuild, as discussions about management and roster changes persist amid their underwhelming performance.