Lionel Messi's potential absence due to a leg injury casts uncertainty over Argentina's Copa America quarterfinal match, although the team remains a favorite. Other powerhouses like Uruguay and underdogs such as Ecuador, Venezuela, and Canada add intrigue to the tournament's knockout stage. Despite Messi not scoring, players like Lautaro Martinez and Julián Álvarez have stepped up for Argentina. Meanwhile, Uruguay's Darwin Nunez shines, setting up an exciting clash with Brazil. The quarterfinals present opportunities for unexpected outcomes as lesser-known teams like Venezuela and Panama aim to make their mark.