The Melbourne Cup has faced significant disruptions due to veterinary assessments, leading to the withdrawal of several contenders. Athabascan has been withdrawn due to cardiac arrhythmia following recommendations from equine specialists, prioritizing safety for the horse. High-profile contender Onesmoothoperator is undergoing further vet checks after sustaining a cut, casting doubt on his participation in the race. Additionally, the undefeated Irish horse Jan Brueghel has been ruled out after a veterinary examination. The race will still feature a record four female jockeys and notable international competitors, including Vauban, who is favored to win for the second consecutive year. Racing Victoria has emphasized the importance of adhering to veterinary advice to prevent potential tragedies in the sport, recalling previous incidents of horse fatalities in the Cup.