New Insights Deepen US Colorectal Cancer Disparities

Recent studies reveal that while colorectal cancer screening rates have risen among adults aged 45 to 49, adenoma detection rates remain slightly lower compared to older age groups. Marital status has emerged as a significant factor in survival, with married individuals experiencing better outcomes than their unmarried peers. Early-life high BMI is now linked to a greater risk of developing colorectal cancer later in life. Additionally, a lifestyle-based 10-year risk prediction model has been validated in China, enabling earlier risk stratification. Racial minorities, including Black, Asian, American Indian/Alaskan Native, and Hispanic populations, continue to be disproportionately diagnosed with early-onset colorectal cancer at more advanced stages. These findings highlight the ongoing need for equitable early detection strategies and interventions.