David Duchovny, in his new movie 'Reverse the Curse,' portrays a sick Red Sox fan whose condition worsens with his team's losses, using humor to address aging and mortality by showcasing a nude scene with co-star Logan Marshall-Green. Duchovny emphasized the importance of humor in dealing with life's challenges, finding comedy in discussing aging bodies and mortality. The film explores themes of reconciliation and reversing personal curses within a father-son relationship amid the backdrop of the Red Sox 'curse of the Babe.' Duchovny's multifaceted career and creative endeavors, including podcasting and music, reflect his fascination with the concept of losing and exploring deeper themes through his work.