The Detroit Lions' practice on Wednesday was notably affected by injuries and illnesses. Linebacker Alex Anzalone missed practice due to a concussion sustained in Week 2, with uncertainty surrounding his availability for the upcoming game unless he shows limited participation later in the week. Rookie cornerback Terrion Arnold also sat out due to an illness but appears to have recovered from a prior finger injury, leaving his status for Sunday pending. Head coach Dan Campbell expressed concern over Anzalone's potential absence, highlighting Jack Campbell's readiness to step up if needed. Additionally, several other players, including Graham Glasgow, Ifeatu Melifonwu, and Ennis Rakestraw, were sidelined, while Marcus Davenport and Amon-Ra St. Brown returned as full participants. The Lions will need to monitor these injuries closely as they prepare for their match against Arizona.