Massachusetts Infant Hospitalized With Suspected Powassan Virus

A one-month-old baby, Lily Sisco, from Martha’s Vineyard is in serious condition at Massachusetts General Hospital after likely contracting Powassan virus from a tick bite during a walk near her home. Powassan virus is a rare but potentially fatal tick-borne disease with no specific treatment that can cause brain inflammation, seizures, and long-term neurological complications, particularly in infants and the elderly. In 2024, there have been three confirmed Powassan cases in Massachusetts and 24 nationwide, though health officials believe unrecognized cases may make the true number higher. According to the CDC, just under 400 U.S. cases have been recorded over the past 20 years, with a mortality rate between 10 and 13 percent. Lily is receiving intensive care and is showing progress, but her long-term prognosis is still unclear. Health experts urge the public to take precautions against ticks during this especially severe season, recommending 30% DEET-based repellents and careful tick checks.