In a dominant performance, the Cleveland Guardians defeated the Pittsburgh Pirates 6-1, with rookie Kyle Manzardo hitting his first two major league home runs. Manzardo, who was recalled from Triple-A Columbus, homered in the fourth and sixth innings against Pirates starter Mitch Keller. In addition to Manzardo, José Ramírez and Andrés Giménez also contributed home runs, bringing the Guardians' total to four in the game. Pitcher Alex Cobb had a strong outing, allowing only one unearned run over six innings before his perfect game bid was broken up. The Guardians now lead the AL Central by 3.5 games over Kansas City and Minnesota, improving their impressive home record to 43-25. This victory highlights the impact of roster changes made ahead of the expanded rosters on September 1.