The LSU Tigers secured a 44-21 victory over Nicholls State in their home opener, despite experiencing significant challenges, particularly in the first half. Quarterback Garrett Nussmeier threw a career-high six touchdown passes, tying him with past LSU greats for the impressive feat. Nicholls State, a 47-point underdog, managed to keep the game competitive, with running back Collin Guggenheim rushing for 145 yards and two touchdowns, including a 67-yard score that narrowed the lead to just two points early in the third quarter. However, LSU responded with 21 unanswered points to secure the win. Head Coach Brian Kelly acknowledged the physical play of Nicholls but emphasized the need for his team to improve, especially after being outperformed in rushing yards. The Tigers will need to address their running game struggles as they move forward in the season.