The Kansas City Chiefs, led by Patrick Mahomes, are aiming for an unprecedented third consecutive Super Bowl victory, a feat never achieved in NFL history. They are heavily favored to win the Super Bowl again, drawing significant bets ahead of the season. The San Francisco 49ers, last year's runner-ups, are positioned as the second favorites but face challenges, including contract disputes impacting key players. The Detroit Lions, who surprised the Chiefs in their season opener, are also seen as strong contenders following a 12-win season. Other notable storylines include the return of Aaron Rodgers with the Jets, the Bears' rookie quarterback Caleb Williams, and the restructured AFC West teams, all trying to dethrone the Chiefs. The Kansas City franchise has dominated the AFC West since 2016 and continues to be a focal point of the NFL season.