Cardinals' James Conner Carted Off With Serious Ankle Injury Against 49ers

Arizona Cardinals star running back James Conner suffered a severe lower-body injury during their Week 3 game against the San Francisco 49ers, resulting in him being carted off the field and ruled out for the remainder of the game. The injury, described by the team as affecting his right ankle or knee, appeared serious as Conner's leg twisted awkwardly during a tackle, prompting players from both teams to gather around him in support. Conner, a two-time Pro Bowler and a key figure in the Cardinals' rushing attack with multiple 1,000-yard seasons, has a history of leg injuries, including previous knee and ankle issues. His absence poses a significant challenge for Arizona's offense, with backups like Trey Benson expected to take on a larger role. The team has yet to disclose the full extent of the injury, but there are concerns it could be season-ending. The incident highlights the physical toll of the NFL season and the impact of key player injuries on team dynamics.