OneBlood, a nonprofit blood donation center serving the southeastern United States, has been hit by a ransomware cyberattack, significantly impacting its operations. The attack has affected OneBlood's software system, forcing the organization to implement slower manual processes and greatly reducing its capacity to collect, test, and distribute blood. Despite these challenges, OneBlood remains operational with the support of cybersecurity experts and various federal, state, and local agencies. The nonprofit has issued an urgent call for blood donations, especially for O Positive, O Negative, and Platelet types, and has asked over 250 hospitals it serves to activate their critical blood shortage protocols. Blood centers across the country and the AABB Disaster Task Force are sending additional blood products to assist OneBlood during this crisis. The nonprofit assures that donors' personal information has not been compromised.