The New England Patriots are set to begin their first season without Bill Belichick, with Jerod Mayo stepping in as head coach and Jacoby Brissett starting at quarterback. The team faces significant injury challenges, including offensive linemen Sidy Sow and Vederian Lowe, and running back Antonio Gibson. Meanwhile, the Cincinnati Bengals are optimistic as quarterback Joe Burrow begins the season healthy, although star receiver Ja'Marr Chase is questionable due to limited practice time amidst contract negotiations. The Patriots have revamped their roster with 28 new players, including 10 rookies, and will rely on controlling the line of scrimmage to succeed. The Bengals, with a 1-4 record in openers under coach Zac Taylor, aim to capitalize on the Patriots' unsettled offensive line and injury issues.