Sasha Calle, who portrayed Supergirl in The Flash, expressed her heartbreak over losing the role she was initially set to reprise in multiple films. Despite signing a multi-picture deal and having deep attachments to the character, Calle faced disappointment as the newly rebooted DC Universe, led by James Gunn and Peter Safran, opted for Milly Alcock to take over the role. Calle reflected on her experience, acknowledging the beauty of representing a queer Latina superhero, stating that her portrayal resonated with many fans. She also revealed that the film's ending was altered, removing a planned interaction between her Supergirl and Michael Keaton's Batman. Calle remains proud of her performance and the significance of her role despite the challenges faced during production. The new Supergirl film is expected to be part of the DCU's upcoming slate set to commence with Superman in 2025.