The Substance, a new body horror film that premiered at Cannes, revolves around a fading TV star, Elisabeth Sparkle (Demi Moore), who uses a mysterious drug to create a younger version of herself, Sue (Margaret Qualley). Both actresses described the demanding shoot as 'brutal,' with Moore experiencing significant stress and health issues during production. The film explores themes of aging, beauty standards, and internalized misogyny, and has sparked controversy for its graphic violence and nudity. Directed by Coralie Fargeat, the film employs exaggerated imagery and dark satire to critique Hollywood's unrealistic expectations of women. Critics have praised Moore's performance and the film's unique approach to its subject matter, suggesting it could lead to award nominations. Ultimately, The Substance serves as a disturbing commentary on the lengths people will go to for youth and beauty, while also reflecting on self-worth and societal perceptions.