Boston's Jarren Duran, named All-Star MVP, hit a decisive two-run home run in the fifth inning, leading the American League to a 5-3 victory over the National League in the MLB All-Star Game. Pittsburgh rookie Paul Skenes pitched a hitless first inning for the NL, while Shohei Ohtani of the Dodgers hit a three-run homer to initially put the NL ahead 3-0. Juan Soto tied the game with a two-run double and scored on David Fry's single. Oakland's Mason Miller earned the win with a 103.6 mph pitch, the fastest in All-Star Game history, and Cleveland's Emmanuel Clase secured the save by striking out two in the ninth. Ohtani’s homer was significant as it made him the first Dodgers player to homer in the All-Star Game since Mike Piazza in 1996.