Patrick Mahomes had a notable performance during the Kansas City Chiefs' game against the San Francisco 49ers, highlighted by a remarkable 1-yard rushing touchdown where he trucked 49ers safety Malik Mustapha, showcasing his physicality typically reserved for running backs. Despite struggling initially with two interceptions in the first half, Mahomes turned the tide in the fourth quarter, marking his first rushing touchdown since Week 16 of the previous season. The game, a rematch since last February's Super Bowl, saw Mahomes facing a tough 49ers defense, which managed to contain him for most of the game until his decisive run. Additionally, Mahomes was on the receiving end of a hit in the throat from defensive tackle Maliek Collins, which went unpenalized, sparking discussions about officiating bias. Ultimately, the Chiefs maintained a narrow lead during a challenging matchup. Mahomes' ability to overcome adversity and physically dominate a defender underscored his unique talents as a quarterback.