The San Francisco 49ers are facing significant challenges in their 2024 NFL season, starting with injuries to key players, including two-time All-Pro running back Christian McCaffrey and star receiver Deebo Samuel. McCaffrey has been placed on injured reserve with calf and Achilles issues, while Samuel is expected to miss several weeks due to a calf strain. After a disappointing loss to the Minnesota Vikings, the 49ers' quarterback Brock Purdy is under increased pressure to lead the team effectively. Purdy has shown improvement in his leadership, which is vital given the team's current struggles, according to coaches and teammates. Former quarterback Steve Young suggested that Purdy should incorporate more rushing into his game to diversify the offense. With both McCaffrey and Samuel sidelined, the 49ers will need a collective team effort to fill the void left by their absence.