The Los Angeles Rams faced significant injuries in their season opener against the Detroit Lions, where they lost 26-20 in overtime. Four of their top six offensive linemen were injured, including center Steve Avila, who will be placed on injured reserve with an MCL sprain. Star receiver Puka Nacua also reaggravated a knee injury and will be sidelined for the foreseeable future. Coach Sean McVay expressed determination to move forward despite the setbacks, reflecting on the team's previous struggles with injuries last season. The Rams are now winless heading into their Week 2 match against the Arizona Cardinals, with hopes of recovery amidst ongoing injury challenges. Notably, the offensive line will remain under pressure as they adapt to the absence of key players.