Aubrey Plaza revealed on the Howard Stern Show that she suffered a stroke at age 20, which left her briefly paralyzed and unable to speak. The incident occurred mid-sentence while she was visiting friends, and she initially struggled to distinguish between her right and left sides, leading doctors to diagnose the stroke. Plaza attributes the stroke to her use of birth control pills, a factor she no longer exposes herself to. Despite the terrifying experience, which included paramedics suspecting drug use, she underwent cognitive therapy and has since experienced minor strokes known as transient ischemic attacks. This health scare has profoundly impacted her perspective on life, making her more appreciative of its fragility and motivating her to stay busy and make the most out of each day.